Beyond Apoptosis: Cellular Outcomes of Cancer Therapy

Addressing a major field of interest for oncologists, cell biologists, and other biomedical researchers, Beyond Apoptosis provides an overview of how different biological mechanisms of cell death, senescence and mitotic catastrophe stop the growth of tumor cells treated with anticancer agents.

Written by internationally renowned contributors, this text includes:

• morphological illustrations, as well as a DVD containing documents and video clips from various time-lapse microscopic studies of cell death and mitotic catastrophe


• the role and limitations of apoptosis as a determinant of the toxicity of anticancer agents


• alternative mechanisms of the antiproliferative actions of anticancer drugs and radiation, such as non-apoptotic cell death, cell senescence, and mitotic catastrophe


• non-apoptotic forms of cell death, such as necrosis, paraptosis, autophagic cell death, and others


• morphological and kinetic differences of the various forms of cell death