Copper is increasingly recognized for its possible role in the prevention and moderation of disease, as well as the treatment of a number of conditions including skin irritation, sensitization, rheumatoid arthritis, and other inflammatory conditions. This source reviews general principles of percutaneous penetration to clarify the mechanisms controlling anti-inflammatory activity, dermal sensitivity, and the absorption of copper compounds in the human body and the effects of these functions on healthy skin and human health.

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