Epidemiological studies have found that drugs are now the most common cause of liver failure in the United States, and the past decade has seen an explosion of new information concerning the immunology, toxicology, and pharmacology of drug-induced liver disease. This expertly written Second Edition supplies an in-depth discussion of the recent developments in drug-induced hepatotoxicity, covering mechanisms, histopathology, management, risk factors, and patterns of drug and toxin-induced liver disease.