The book essentially covers how to code up a large application without a framework. In reality if you are working with a large application (or not) you should use an existing framework to manage PHP, HTML templates, and JavaScript. For example CodeIgniter, (I haven't found a PHP HTML templating system I like yet), and Dojo.



tl;dr - has some stuff you should know, but better to let a framework(s) do it for you.

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