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Enantiomer Separation: Fundamentals and Practical Methods

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Enantiomer Separation: Fundamentals and Practical Methods

Many important pharmaceutical drugs, chemicals for the organic synthesis of chiral compounds, electronic elements such as liquid crystals, and polymeric materials are chiral (enantiomeric). The development of new practical methods for the preparation of enantiomerically pure substances is thus vital. Enantiomer Separation is written by several experts working in modern enantiomer separation chemistry who understand the needs of the many scientific and engineering chemists who need a cost-efficient supply of optically active materials of high quality. This book contains the following modern practical methods of enantiomer separation:
  • Inclusion complexation of a racemic compound with a chiral host compound, which gives chiral host-chiral guest inclusion compounds, from which the chiral guest can be obtained. When this separation is combined with distillation technique, for example, enantiomer separation can be accomplished by fractional distillation in the presence of a chiral host compound. This is a modern and
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