Clostridia is one of the largest bacterial genera with an enormous potential for biotechnical and medical applications. Despite this scientific, medical, and industrial interest, information on basic methods, biochemical fundamentals, clinical practice, industrial applications, and novel developments is scattered in a variety of research articles, reviews, and book chapters. The Handbook on Clostridia combines all these topics in a single volume. The author has taken a global approach, integrating into a seamless entity what until now have been two disparate and separate fields: Clostridia of biotechnological importance and Clostridia of medical importance.