Computational Molecular Biology: An Introduction

This book is not very good as an introduction. First read some other book such as Setubal and Meidanis, "Introduction to Computational Molecular Biology"; or Krane & Raymer, "Fundamental Concepts of Bioinformatics". These books have more readable narrative and examples.

The writing in this book is obtuse. It is written like an advanced abstract math book, not like an ostensibly applied science book. The notation is unnecessarily intricate. Even though it says "Introduction" in the title, there are very few tutorial examples. This is just for mathematicians/computer scientists: no biologist I have ever known would/could read this and really understand the algorithms.

This book does, however, have one of the more complete detailed descriptions of various algorithms used for sequence matching, etc. If you have read some other books and are looking for more details on algorithms, then this is your book. But I'm still waiting for THE ultimate Computational Biology book!