This volume contains selected essays of Manfred M. Fischer in the field of spatial analysis from the perspective of GeoComputation. The volume is structured in four parts. The first sets the context by dealing with broad issues related with spatial analysis and the role of GIS. The second relates to computational intelligence technologies such as neural networks that provide a new style of performing spatial modelling and analysis tasks in geography and other spatial sciences. The third part provides the theoretical framework required and displays the efficient use of various adaptive pattern classifiers in remote sensing environments. The final part outlines the latest, most significant developments in neural spatial interaction modelling.