The three-volume set, LNCS 2329, LNCS 2330, and LNCS 2331, constitute the refereed proceedings of the Second International Conference on Computational Science, ICCS 2002, held in Amsterdam, The Netherlands, in April 2002. The three volumes present more than 350 reviewed contributed and invited papers and span the whole range of computational science, from foundational issues in computer science and mathematics to advanced applications in virtually all application fields making use of computational techniques. These proceedings give a unique account of recent results in the field.