As the number of commercially available instruments having atmospheric pressure ionization (API) interfaces has increased, interest in liquid chromatography/mass spectrometry (LC/MS) for lipid analysis has blossomed. Research into novel techniques for LC/MS is a lively source of journal article material, most notably regarding electrospray ionization and atmospheric pressure chemical ionization for analysis of lipids. Growing interest in modern API techniques for lipid analysis precipitated publication of this volume. The summary of LC/MS in this book will serve as a valuable reference and resource for those interested in moving into the field of lipid analysis using modern instrumentation. Modern Methods describes previous work that helped established the foundation of the field, while also demonstrating new data that is quickly defining a new level of "state-of-the-art." Described herein are the methods that will be applied to lipids into the next decade and hopefully beyond.