The ISAAC (International Society for Analysis, its Applications and Computation) Congress, which has been held every second year since 1997, covers the major progress in analysis, applications and computation in recent years. In this proceedings volume, plenary lectures highlight the recent research results, while 17 sessions organized by well-known specialists reflect the state of the art of important subfields. This volume concentrates on partial differential equations, function spaces, operator theory, integral transforms and equations, potential theory, complex analysis and generalizations, inverse problems, functional differential and difference equations and integrable systems.