This volume is the latest in a prominent biannual series of scientific meetings on the exciting research topics of dark matter and, more recently, of dark energy. It contains a state-of-the-art update on detection efforts by experimental groups around the world trying to pin down exotic new forms of matter under the names of axions, neutralinos, wimps, primordial black holes, q balls, sterile neutrinos, as well as a tantalizing new form of dark energy component called phantom energy and quintessence. The book is self-contained as it also includes general reviews on recent cosmological observations-supernovae measurements, cosmic matter distribution surveys and cosmic radiation anisotropies-introducing even the uninitiated reader to this fascinating frontier of research.