This book reflects the meteoric increase in knowledge regarding bone remodeling including molecular understanding of osteoclast development, regulatory molecules such as cytokines, pathophysiology and pharmaceutical development to treat osteoclast function. Rapid publication of an up-to-date volume addressing these issues by experts in the field, an asset to any library of clinical endocrinologists and rheumatologists, will be a valuable read for those entering the scientific arena of bone remodeling research. It will integrate recent technological advances with foundation data to provide a comprehensive view of bone resorption, and in addition will link information gained from the genetic and molecular to the physiological and clinical levels This volume is addressed to clinical practitioners, nutrition scientists, researchers and students, who seek a fundamental understanding of this important subject. An invaluable publication for the community of medical specialists- internists, endocrinologists, nephrologists, orthopaedists- as well as dental, paramedical, nursing and veterinary practitioners. Useful also for those entering the field of bone biology, as well as those on the research/clinical interface who find it difficult to find a complete series to bring them ?up to speed? with technological advancements in this area.