The failure of all attempts to unify gravitation with other fundamental interactions has lead to an abandonment of point particles and differentiable spacetime of General Relativity and Quantum Theory, including Quantum Field Theory. While Quantum Superstrings (or M-Theory) and other Quantum Gravity approaches work with a lattice like structure or extended objects, several unanswered questions remain.The book describes another approach in which oscillators at the Planck scale from a background Quantum Vacuum are fundamental. We describe how this leads to the formation of the elementary particles, and also a cosmology that correctly predicted an accelerating Universe with a small cosmological constant, apart from other things.In this context the nature of spacetime and gravitation are reexamined. While it is argued that spacetime has a chaotic underpinning on the one hand, gravitation has a distributional character on the other. It is shown how all these considerations are not only consistent but also explain several, otherwise unanswered features. Finally experimental tests for the near future are also discussed.