The SSRIs have had a major impact on the treatment of depression and one, Prozac, has even attained cult status. Yet, their predecessors are still used with impunity and we have no definitive explanation for their therapeutic effects. In reviewing the established and novel indications for treatment with these drugs, SSRIs: Past, Present and Future, incorporates a frank and detailed appraisal of their safety, efficacy and tolerability as well as exploring their underlying neurobiology.

This book is specifically designed to be accessible and instructive to both students and experts in the clinical and preclinical sciences. Whenever feasible, individual chapters integrate material from these two areas and they all start by outlining the background to each topic before discussing more specialized research. As a result, readers who are dedicated to one of branch of this field will be encouraged to increase their understanding of, and interest in, others.