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libcats.org
Common Thread: A Story of Science, Politics, Ethics and the Human GenomeJohn Sulston, Georgina FerryThe world was agog when scientists made the astounding announcement that they had successfully sequenced the human genome. Few contributed so directly to this feat as John Sulston. This is his personal account of one of the largest international scientific operations ever undertaken. It was a momentous occasion when British scientist John Sulston embarked on the greatest scientific endeavor of our times: the sequencing of the Human Genome. In The Common Thread, Sulston takes us behind the scenes for an in-depth look at the controversial story behind the headlines. The accomplishments and the setbacks-along with the politics, personalities, and ethics-that shaped the research are frankly explored by a central figure key to the project. From the beginning, Sulston fervently proclaimed his belief in the free and open exchange of the scientific information that would emerge from the project. Guided by these principles, The Human Genome Project was structured so that all the findings were public, encouraging an unparalleled international collaboration among scientists and researchers. Then, in May 1998, Craig Venter announced that he was quitting the Human Genome Project-with plans to head up a commercial venture launched to bring out the complete sequence three years hence, but marketed in a proprietary database. Venter's intentions, clearly anathema to Sulston and the global network of scientists working on the Project, marked the beginning of a dramatic struggle to keep the human genome in the public domain...
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