The fourth edition of The Management of Sickle Cell Disease - developed by physicians, nurses, psychologists, and social workers who specialize in the care of children and adults with sickle cell disease - describes the current approach to counseling and also to management of many of the medical complications of sickle cell disease. It is organized into four parts: Diagnosis and Counseling, Health Maintenance, Treatment of Acute and Chronic Complications, and Special Topics. Multiple new therapies are now available for children and adults with sickle cell disease, and often the options to be chosen present a dilemma for both patients and physicians. This book does not provide answers to many of these newer questions but rather explains the choices available. It is to serve as an adjunct to recent textbooks that delve more deeply into all aspects of the disorder. NIH Publication.