Describes the combinations of standard & special microbiological practices, safety equip., & facilities which are recommended for work with a variety of infectious agents in various labs. This revision takes into account such issues as global concern about emerging & reemerging infectious diseases; increased interest in prion diseases with the identification of BSE in England; the occurrence of several lab-associated infections; increased concern regarding the national & intl. transfer of infectious microorganisms; & growing concerns about bioterrorism, & the increased security needs of our microbiological labs.