Chiral Pollutants: Distribution, Toxicity and Analysis by Chromatography and Capillary Electrophoresis
Imran Ali, Hassan Y. Aboul-Enein
The chiral analysis of environmental pollutants is a fairly recent development and attracts scientists needing to investigate the toxicity of enantiomers. For example, approximately 250f agrochemicals are chiral in nature, including pesticides that are applied as their racemates in agricultural and forestry activities. To predict the exact toxicity of pollutants the determination of the concentration of both enantiomers in environmental matrices is essential. Various approaches to chiral resolution have been developed for the analysis of pharmaceuticals and drugs but this is the first text to present detailed metholodology on the chiral separation of pollutants.This book is divided into 10 chapters: the first is an introduction to the principles of chirality; Chapters 2 to 9 discuss the sources, distribution, biotransformation, toxicity, sample preparation and chiral resolution of environmental pollutants by chromatography and capillary electrophoresis. In addition, the optimization of experimental parameters for chromatographic and capillary electrophoretic techniques is presented, making this book a useful 'how to' guide to chiral pollutants analysis. Coverage of the types, structures and properties of chiral stationary phases and their applications for the analysis of chiral pollutants is also presented. The concluding chapter reports on chiral legislation globally, and presents perspectives which could guide future research in this area.This book will be of interest to researchers in biology, analytical chemistry and the environmental in industry, academia and governmental regulatory agencies.
