This book offers a systematic and comprehensive exposition of the quantum stochastic methods that have been developed in the field of quantum optics. It includes new treatments of photodetection, quantum amplifier theory, non-Markovian quantum stochastic processes, quantum input-output theory, and positive P-representations. It is the first book in which quantum noise is described by a mathematically complete theory in a form that is also suited to practical applications. Special attention is paid to non-classical effects, such as squeezing and antibunching. This second edition has been enlarged so as to take account of rapid progress in the field, and now includes two additional chapters, on the stochastic Schrodinger equation and on cascaded quantum systems.